WISE
Chromatic Pupillometry to Target Photoreceptor Families
WISE, is an innovative device designed to exploit specifically triggered patient’s pupil dynamics to evaluate and support early diagnosis.
WISE Stands Out
Objective Eye Evaluation
WISE uses advanced opto-perceptive principles, including metamers and silent substitution techniques, to selectively assess retinal functions and evaluate visual health with unparalleled precision.
WISE provides invaluable insights for clinicians. By analyzing the patient’s pupil diameter in response to specific light stimuli, WISE offers insights that are valuable and crucial for clinicians in their diagnostic and treatment decisions1.
Tailored Bilateral Assessments
Maxwellian optical arrangement ensures solid and artefact-free pupil diameter measurements. The complete independent bilateral eye stimuli enhance assessment accuracy.
Advanced technologies guarantee precise measurements for informed decision-making.
Tailor-Made Protocols
Researchers and clinicians benefit from a high degree of flexibility, enabling them to fully customize eye stimuli for tailor-made protocols meeting individual needs.
The customizable feature ensures personalized care and projects optimized treatment monitoring.
Regulatory Compliance
WISE is a certified CE-marked Class I medical device meeting rigorous regulatory standards to guarantee safety and performance.
You can trust WISE’s cutting-edge technology to deliver accurate eye stimuli and, consequently, collect reliable pupil dynamics data in timely, safe, and regulatory-compliant clinical sessions.
Ease of Use
WISE is ergonomically designed to maximize comfort, ensuring a seamless patient and clinician experience.
Its straightforward operation simplifies alignment and usage, enhancing clinical data quality and efficiency.
Metamer Opportunities
The figure shows the CIE chromaticity diagram obtained by WISE, which can be used to investigate the eye’s fundus photoreceptor cells.
The power of the instrument enables it to deceive the patient’s perception by presenting stimuli that are perceived as identical in color and intensity, but which are fundamentally different – a metamer. Such advanced stimulations allow to asses the functionalities of rods, cones, and melanopsin-containing retinal ganglion cells (mRGCs) in a selective fashion, engaging a specific contrast between photoreceptor families2.
References
- Conus V., Geiser M. A Review of Silent Substitution Devices for Melanopsin Stimulation in Humans. Photonics. 2020; 7(4):121
- Evéquoz, G. et al. Maximum Possible Contrast Level for Silent Substitution: A Theoretical Model Applied to Melanopsin Stimulation. JOSA A. 2021; (9): 1312–1938
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